| 1 | 57.04 | Angela MongitorePlainedge | Plainedge '11 | Molloy College Indoor Invitational | 2014 |
| 2 | 59.24 | Cassandra JeanEast Meadow | East Meadow '10 | St. John's University Bill Ward Invitational | 2013 |
| 3 | 1:00.3 | Cara Lee KepplerOceanside | Oceanside '09 | Crossover #3 | 2007 |
| 4 | 1:01.4 | Kendrea AikeisWestbury | Westbury '07 | Crossover #3 | 2007 |
| 5 | 1:01.61 | Danielle ParkerMepham | Mepham '10 | Molloy College Indoor Invitational | 2014 |
| 6 | 1:01.9 | Jennifer KornblauHewlett | Hewlett '07 | Crossover #3 | 2007 |
| 7 | 1:02.32 | Mary CamaranoKellenberg | Kellenberg '13 | St. John's University Bill Ward Invitational | 2014 |
| 8 | 1:02.47 | Ashe DavisRoosevelt | Roosevelt '14 | St. John's University Bill Ward Invitational | 2015 |
| 9 | 1:02.8 | Racquel AndersonHempstead | Hempstead '06 | Crossover #6 | 2004 |
| 10 | 1:02.91 | Nicolette AgostinacchioMacArthur | MacArthur '16 | St Joseph's College Indoor Invitational | 2018 |
| 11 | 1:03.2 | Nickesha WilliamsUniondale | Uniondale '05 | Crossover #6 | 2004 |
| 12 | 1:03.27 | Pollyanna VelascoHoly Trinity | Holy Trinity '14 | St. John's University Bill Ward Invitational | 2014 |
| 13 | 1:03.3 | Jennifer MounessaGreat Neck North | Great Neck North '07 | Crossover #3 | 2007 |
| 14 | 1:04.0 | Patricia McNishManhasset | Manhasset '09 | Crossover #3 | 2007 |
| 15 | 1:04.1 | Tamara MeyerGreat Neck North | Great Neck North '08 | Crossover #3 | 2007 |
| 16 | 1:04.12 | Aleisha JeffersUniondale | Uniondale '14 | St. John's University Bill Ward Invitational | 2014 |
| 17 | 1:04.2 | Elena KatsikisGarden City | Garden City '05 | Crossover #6 | 2004 |
| 18 | 1:04.7 | Samantha BeimMepham | Mepham '09 | Crossover 3 Conferences 1 | 2008 |
| 19 | 1:04.9 | Paige McAteeMassapequa | Massapequa '09 | Crossover 3 Conferences 1 | 2008 |
| 20 | 1:04.90 | Arianna HenryVal Stream Central | Val Stream Central '28 | USATF Long Island Youth Indoor Track & Field Championships | 2023 |
| 21 | 1:05.0 | Kristin MobyedMineola | Mineola '07 | Crossover Meet #5 | 2005 |
| 22 | 1:05.01 | Ena OtakaPlainview | Plainview '12 | St. John's University Bill Ward Invitational | 2014 |
| 23 | 1:05.1 | Emily LipariRoslyn | Roslyn '10 | Crossover #3 | 2007 |
| 24 | 1:05.1 | Shannon RogersMassapequa | Massapequa '06 | Crossover #6 | 2004 |
| 25 | 1:05.1 | Nina KucharczykManhasset | Manhasset '09 | Crossover #3 | 2007 |
| 26 | 1:05.3 | TrudiAnn CoverHempstead | Hempstead '05 | Crossover #6 | 2004 |
| 27 | 1:05.33 | Johane AccimeSewanhaka | Sewanhaka '11 | Molloy College Indoor Invitational | 2014 |
| 28 | 1:05.4 | Brooke SenkenGarden City | Garden City '08 | Crossover #6 | 2004 |
| 29 | 1:05.4 | Victoria ChementoGarden City | Garden City '10 | Crossover #3 | 2007 |
| 30 | 1:05.4 | Danielle MarshallBaldwin | Baldwin '07 | Crossover #3 | 2007 |
| 31 | 1:05.4 | Olivia AmatoManhasset | Manhasset '09 | Crossover 3 Conferences 2 | 2008 |
| 32 | 1:05.41 | Katherine KellyManhasset | Manhasset '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 33 | 1:05.5 | Courtney KellyMepham | Mepham '08 | Crossover 3 Conferences 1 | 2008 |
| 34 | 1:05.5 | Sara AlpertEast Meadow | East Meadow '09 | Crossover 3 Conferences 2 | 2008 |
| 35 | 1:05.7 | Haleigh LesterJFK Bellmore | JFK Bellmore '07 | Crossover #3 | 2007 |
| 36 | 1:05.77 | Megan ReillyManhasset | Manhasset '21 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 37 | 1:05.8 | Samantha ZeeLynbrook | Lynbrook '08 | Crossover 3 Conferences 1 | 2008 |
| 38 | 1:05.9 | Heidi PaulUniondale | Uniondale '07 | Crossover #6 | 2004 |
| 39 | 1:05.9 | Victoria VogelCold Spring Harbor | Cold Spring Harbor '07 | Crossover Meet #5 | 2005 |
| 40 | 1:06.0 | Courtni WalkerUniondale | Uniondale '07 | Crossover #6 | 2004 |
| 41 | 1:06.1 | Victoria ChimentoGarden City | Garden City '10 | Crossover 3 Conferences 1 | 2008 |
| 42 | 1:06.1 | Krissy MajkowskiEast Meadow | East Meadow '07 | Crossover #3 | 2007 |
| 43 | 1:06.2 | Tracy MessiasUniondale | Uniondale '06 | Crossover #6 | 2004 |
| 44 | 1:06.2 | Lauren MobyedMineola | Mineola '07 | Crossover Meet #5 | 2005 |
| 45 | 1:06.4 | Elizabeth HenryMassapequa | Massapequa '09 | Crossover #3 | 2007 |
| 46 | 1:06.6 | Ketsia Saint-ArmandSewanhaka | Sewanhaka '10 | Crossover 3 Conferences 1 | 2008 |
| 47 | 1:06.6 | Rose KennedyPlainedge | Plainedge '06 | Crossover Meet #5 | 2005 |
| 48 | 1:06.6 | Alistaire McDonoughGarden City | Garden City '05 | Crossover #6 | 2004 |
| 49 | 1:06.7 | Jennifer FloresEast Meadow | East Meadow '10 | Crossover 3 Conferences 2 | 2008 |
| 50 | 1:06.8 | Devon LawrenceManhasset | Manhasset '09 | Crossover 3 Conferences 2 | 2008 |
| 51 | 1:06.8 | Tijen OzcanSyosset | Syosset '07 | Crossover #3 | 2007 |
| 52 | 1:06.9 | Annmarie CharnoPlainedge | Plainedge '09 | Crossover 3 Conferences 1 | 2008 |
| 53 | 1:06.9 | Jessica LevyOceanside | Oceanside '07 | Crossover #3 | 2007 |
| 54 | 1:06.9 | Jessica MounessaGreat Neck North | Great Neck North '08 | Crossover #3 | 2007 |
| 55 | 1:07.05 | Giuliana SteinManhasset | Manhasset '20 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 56 | 1:07.1 | Brianna CanoValley Stream North | Valley Stream North '09 | Crossover 3 Conferences 2 | 2008 |
| 57 | 1:07.1 | Lauren DyerValley Stream North | Valley Stream North '07 | Crossover Meet #5 | 2005 |
| 58 | 1:07.14 | Cecelia CapozzoliSacred Heart | Sacred Heart '12 | Molloy College Indoor Invitational | 2014 |
| 59 | 1:07.2 | Maeve McGillowayNorth Shore | North Shore '06 | Crossover Meet #5 | 2005 |
| 60 | 1:07.21 | Ashley PickettUniondale | Uniondale | USATF Long Island Open & Masters Indoor Track & Field Championships | 2024 |
| 61 | 1:07.26 | Charlene HickeyEast Meadow | East Meadow '14 | St Joseph's College Indoor Invitational | 2016 |
| 62 | 1:07.30 | Allison TorlincasiFarmingdale | Farmingdale '10 | St. John's University Indoor Track Meet | 2010 |
| 63 | 1:07.3 | Adriana ArguellesEast Meadow | East Meadow '09 | Crossover #3 | 2007 |
| 64 | 1:07.3 | Laura GalloValley Stream South | Valley Stream South '09 | Crossover 3 Conferences 2 | 2008 |
| 65 | 1:07.5 | Michele GriecoMassapequa | Massapequa '07 | Crossover #3 | 2007 |
| 66 | 1:07.5 | Emily BrennerCold Spring Harbor | Cold Spring Harbor '09 | Crossover #3 | 2007 |
| 67 | 1:07.6 | Deanna CerianoGarden City | Garden City '09 | Crossover 3 Conferences 1 | 2008 |
| 68 | 1:07.6 | Desirie SkeeteWestbury | Westbury '07 | Crossover #6 | 2004 |
| 69 | 1:07.7 | Rachel LermanHewlett | Hewlett '05 | Crossover Meet #5 | 2005 |
| 70 | 1:07.7 | Luisa EcheverriEast Meadow | East Meadow '11 | Crossover 3 Conferences 2 | 2008 |
| 71 | 1:07.9 | Alyssa KildareFarmingdale | Farmingdale '08 | Crossover #3 | 2007 |
| 72 | 1:08.0 | Cara MattsonEast Meadow | East Meadow '09 | Crossover 3 Conferences 2 | 2008 |
| 73 | 1:08.1 | Bridget FariaEast Meadow | East Meadow '09 | Crossover 3 Conferences 2 | 2008 |
| 74 | 1:08.13 | Catherine CookeKellenberg | Kellenberg '20 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 75 | 1:08.15 | Shania JagdaSyosset | Syosset '22 | Saint Anthony's Developmental Meet 2 | 2019 |
| 76 | 1:08.18 | Mia TalySacred Heart | Sacred Heart '20 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 77 | 1:08.21 | Kee-Ann CayemitteSyosset | Syosset '23 | Saint Anthony's Developmental Meet 2 | 2019 |
| 78 | 1:08.3 | Danielle BrownGreat Neck North | Great Neck North '08 | Crossover Meet #5 | 2005 |
| 79 | 1:08.4 | Mary LesageCalhoun | Calhoun '08 | Crossover #3 | 2007 |
| 80 | 1:08.51 | Destiny ThompsonValley Stream South | Valley Stream South '13 | Molloy College Indoor Invitational | 2014 |
| 81 | 1:08.6 | Lauren BelgraierCalhoun | Calhoun '08 | Crossover #3 | 2007 |
| 82 | 1:08.61 | Akimmie ParkerFarmingdale | Farmingdale | St. John's University Indoor Invitational | 2012 |
| 83 | 1:08.68 | Alexandra PidedjianManhasset | Manhasset '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 84 | 1:08.7 | Valerie SandersEast Meadow | East Meadow '10 | Crossover 3 Conferences 2 | 2008 |
| 85 | 1:08.7 | Adrienne KoslowNorth Shore | North Shore '05 | Crossover Meet #5 | 2005 |
| 86 | 1:08.8 | Limore MeyerGreat Neck North | Great Neck North '10 | Crossover 3 Conferences 2 | 2008 |
| 87 | 1:08.8 | Alexandra OkulaPlainedge | Plainedge '09 | Crossover 3 Conferences 1 | 2008 |
| 88 | 1:08.8 | Courtney PreziosiGarden City | Garden City '05 | Crossover #6 | 2004 |
| 89 | 1:08.8 | Christine CesariniGarden City | Garden City '11 | Crossover #3 | 2007 |
| 90 | 1:08.9 | Caitlin SmithMacArthur | MacArthur '09 | Crossover #3 | 2007 |
| 91 | 1:08.9 | Kristina RollaHewlett | Hewlett '08 | Crossover #3 | 2007 |
| 92 | 1:08.9 | Andreina RoelClarke | Clarke '07 | Crossover #3 | 2007 |
| 93 | 1:08.9 | Nicole TufarielloLynbrook | Lynbrook '08 | Crossover Meet #5 | 2005 |
| 94 | 1:09.0 | Kasey HughesMineola | Mineola '06 | Crossover Meet #5 | 2005 |
| 95 | 1:09.1 | Jessica SchillowValley Stream North | Valley Stream North '08 | Crossover Meet #5 | 2005 |
| 96 | 1:09.1 | Jessica WidmannEast Meadow | East Meadow '11 | Crossover 3 Conferences 2 | 2008 |
| 97 | 1:09.14 | Elizabeth SchmidtKellenberg | Kellenberg '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 98 | 1:09.2 | Kelly SmolenskiNew Hyde Park | New Hyde Park '10 | Crossover Meet #5 | 2005 |
| 99 | 1:09.4 | Sarah AvalloneManhasset | Manhasset '08 | Crossover #3 | 2007 |
| 100 | 1:09.5 | Nathalie MirandaValley Stream North | Valley Stream North '08 | Crossover #3 | 2007 |
