| 1 | 2:05.83 | Charlene LipseyHempstead | Hempstead '09 | Saint Anthony's Invitational | 2009 |
| 2 | 2:08.14 | Emily MengesGarden City | Garden City '10 | Saint Anthony's Invitational | 2009 |
| 3 | 2:09.35 | Emily LipariRoslyn | Roslyn '10 | Saint Anthony's Invitational | 2010 |
| 4 | 2:09.92 | Zaria HallEast Meadow | East Meadow '26 | Section VIII State Qualifer Day 1 | 2025 |
| 5 | 2:10.69 | Maegan KrifchinJFK Bellmore | JFK Bellmore '06 | New York State Track & Field Championships | 2006 |
| 6 | 2:11.01 | Emma GallagherGarden City | Garden City '15 | Saint Anthony's Invitational | 2012 |
| 7 | 2:12.00 | Kristen StuartDivision Avenue | Division Avenue '11 | Stony Brook University - Wolfie Invitational | 2015 |
| 8 | 2:12.06 | Carly KoprowskiGeneral Douglas MacArthur | General Douglas MacArthur | Section VIII State Qualifier | 2023 |
| 9 | 2:12.09 | Ellen ByrnesSacred Heart | Sacred Heart '18 | 47th Saint Anthony's Invitational | 2018 |
| 10 | 2:12.21 | Victoria GuerrierWest Hempstead | West Hempstead '23 | Section VIII State Qualifier | 2022 |
| 11 | 2:12.80 | Maeve GoingSacred Heart Academy | Sacred Heart Academy '26 | NSCHSAA Championships | 2025 |
| 12 | 2:12.87 | Aislinn FrazerFriends Academy (Li) | Friends Academy (Li) '25 | North Shore Invitational | 2025 |
| 13 | 2:13.27 | Jazmine FrayKellenberg | Kellenberg '15 | NSCHSAA League Championships | 2012 |
| 14 | 2:13.38 | Sean YangSyosset | Syosset '26 | North Shore Invitational | 2024 |
| 15 | 2:13.42 | Maureen LewinKellenberg | Kellenberg '19 | Eastern States Invitational | 2018 |
| 16 | 2:13.82 | Reilly SiebertSyosset | Syosset '18 | Section VIII State Qualifier Meet | 2018 |
| 17 | 2:13.84 | DeAnna MartinValley Stream South | Valley Stream South '19 | Section VIII State Qualifier Meet | 2018 |
| 18 | 2:13.99 | Julia SchrieferWheatley | Wheatley '22 | Section VIII State Qualifier | 2022 |
| 19 | 2:14.10 | Kimberly MacKayKellenberg | Kellenberg '11 | League Championships | 2010 |
| 20 | 2:14.96 | Angeline CaamanoManhasset | Manhasset '21 | Section VIII State Qualifier Meet | 2018 |
| 21 | 2:15.01 | Rory HeslinGarden City | Garden City '23 | Section VIII State Qualifier | 2023 |
| 22 | 2:15.14 | Michelle RotondoGarden City | Garden City '11 | Saint Anthony's Invitational | 2010 |
| 23 | 2:15.26 | Valeria PaezGeorge H. Hewlett | George H. Hewlett '27 | Section 8 State Qualifer - Day 1 | 2026 |
| 24 | 2:15.33 | Mackenzie SettonJericho | Jericho '22 | Section VIII State Qualifier | 2022 |
| 25 | 2:15.73 | Isabelle HaroucheCold Spring | Cold Spring '15 | New York State Track & Field Championships | 2014 |
| 26 | 2:15.73 | Kristina CoiroMacArthur | MacArthur '12 | Saint Anthony's Invitational | 2012 |
| 27 | 2:15.83 | Caroline BrownHoly Trinity | Holy Trinity '13 | NSCHSAA League Championships | 2012 |
| 28 | 2:15.88 | Megan JasinskiCold Spring Harbor | Cold Spring Harbor '25 | St. Anthony's Invitational | 2024 |
| 29 | 2:15.9 | Brianna WelchNorth Shore | North Shore '10 | 2009 Nassau Coaches Invitational - Girls | |
| 30 | 2:15.92 | Banker NicoleEast Meadow | East Meadow | SA Inv results 2 | |
| 31 | 2:15.99 | Brianna NerudNorth Shore | North Shore '12 | Saint Anthony's Invitational | 2010 |
| 32 | 2:16.03 | Samantha LawGreat Neck North | Great Neck North '18 | Section VIII County Class 2A - Girls | |
| 33 | 2:16.05 | Shannon McBrienMassapequa | Massapequa '12 | Saint Anthony's Invitational | 2012 |
| 34 | 2:16.44 | Paige DucaSacred Heart | Sacred Heart '15 | Section VIII State Qualifier Meet | 2015 |
| 35 | 2:16.48 | Alyssa GrazianoEast Meadow | East Meadow '09 | Saint Anthony's Invitational | 2009 |
| 36 | 2:16.6 | Jeavon BenjaminHempstead | Hempstead '05 | Division IA Championships | 2005 |
| 37 | 2:16.70 | Rolanda BellSacred Heart | Sacred Heart '05 | Saint Anthony's Invitational | 2005 |
| 38 | 2:16.77 | Sarah SohlFarmingdale | Farmingdale '26 | Section VIII State Qualifer Day 1 | 2025 |
| 39 | 2:17.24 | Ana MarkovinaJericho | Jericho '22 | Section VIII County Championships Class AA | 2022 |
| 40 | 2:17.27 | Isabella SpagnoliGreat Neck South | Great Neck South '25 | Section VIII State Qualifier | 2022 |
| 41 | 2:17.41 | Grace MooreCalhoun | Calhoun '16 | Saint Anthony's Invitational | 2016 |
| 42 | 2:17.44 | Deidre LewinKellenberg | Kellenberg '16 | NSCHSAA League Championships | 2015 |
| 43 | 2:17.5 | Theresa RushValley Stream North | Valley Stream North '06 | State Qualifier | 2005 |
| 44 | 2:17.63 | Ariana MadeiraCold Spring Harbor | Cold Spring Harbor '29 | Nassau Coaches Invitational | 2026 |
| 45 | 2:17.65 | Julia GlenzLong Beach | Long Beach '28 | Section 8 State Qualifer - Day 1 | 2026 |
| 46 | 2:18.03 | Kayleigh JamiesonGeorge H. Hewlett | George H. Hewlett '25 | Section 8 State Qualifier | 2024 |
| 47 | 2:18.09 | Anaya HallEast Meadow | East Meadow '25 | Section VIII State Qualifer Day 1 | 2025 |
| 48 | 2:18.21 | Kayla HawkinsOur Lady of Mercy (Chsaa) | Our Lady of Mercy (Chsaa) '23 | North Shore Invitational | 2023 |
| 49 | 2:18.26 | Ashley CarilloPaul D. Schrieber / Port Washi | Paul D. Schrieber / Port Washi | Nassau Coaches Invitational | 2024 |
| 50 | 2:18.52 | Laura GreeneFriends Acad | Friends Acad '18 | Section VIII State Qualifier Meet | 2018 |
| 51 | 2:18.61 | Joelle FeinbergPort Washington | Port Washington '14 | Saint Anthony's Invitational | 2014 |
| 52 | 2:18.62 | Emily MartinoValley Stream North | Valley Stream North '16 | 98th Annual Port Washington Invitational | 2016 |
| 53 | 2:18.64 | Colleen MeenanKellenberg | Kellenberg '10 | NSCHSAA League Championships | 2009 |
| 54 | 2:18.64 | Taylor MaguireGarden City | Garden City '27 | Nassau Coaches Invitational | 2026 |
| 55 | 2:18.70 | Lucy HurtPort Washington | Port Washington '18 | Section VIII Class 3A County Championships | 2015 |
| 56 | 2:18.83 | Kimora MckayUniondale | Uniondale | Section 8 State Qualifier | 2024 |
| 57 | 2:18.85 | Andrea BourgalMassapequa | Massapequa '12 | Saint Anthony's Invitational | 2012 |
| 58 | 2:18.9 | Jonathan KrammeLynbrook | Lynbrook | Greenand Gold Results | |
| 59 | 2:18.94 | Kelsey GardnerKellenberg | Kellenberg '09 | NSCHSAA League Championships | 2009 |
| 60 | 2:18.94 | Christina DiBernardoSyosset | Syosset '11 | Saint Anthony's Invitational | 2010 |
| 61 | 2:18.99 | Cailey WelchNorth Shore | North Shore '19 | Section VIII State Qualifier Meet | 2015 |
| 62 | 2:19.15 | Elle RichesSacred Heart Academy | Sacred Heart Academy '27 | NSCHSAA Championships | 2025 |
| 63 | 2:19.29 | Katie O'NeillGarden City | Garden City '14 | Girls' Suffolk Coaches Meet | 2010 |
| 64 | 2:19.3 | Cara RostantValley Stream South | Valley Stream South '09 | Class A County | 2007 |
| 65 | 2:19.30 | Morgan NerudNorth Shore | North Shore '16 | Section VIII State Qualifier Meet | 2015 |
| 66 | 2:19.3 | Christina GonzalezValley Stream Central | Valley Stream Central '03 | Class A Counties | 2003 |
| 67 | 2:19.34 | Molly McCannSacred Heart | Sacred Heart '10 | Stony Brook University Track & Field Invitati | 2012 |
| 68 | 2:19.39 | Nicolette AgostinacchioMacArthur | MacArthur '16 | Section VIII Class 3A County Championships | 2015 |
| 69 | 2:19.42 | Charlotte ManogueNorth Shore | North Shore '10 | Saint Anthony's Invitational | 2010 |
| 70 | 2:19.45 | Emily OsmanNorth Shore | North Shore '11 | Saint Anthony's Invitational | 2011 |
| 71 | 2:19.62 | Kaelin McCaffreyOur Lady of Mercy (Chsaa) | Our Lady of Mercy (Chsaa) '24 | St. Anthony's Invitational | 2024 |
| 72 | 2:19.64 | Ashley WongSyosset | Syosset '25 | Section VIII County Championships Class AAA | 2023 |
| 73 | 2:19.89 | Kristina CherringtUniondale | Uniondale '16 | Section VIII Class County Championships | 2014 |
| 74 | 2:19.90 | Kyra Florio-MarinelloMassapequa | Massapequa '26 | Section 8 AAA County Championship | 2026 |
| 75 | 2:20.0 | Tracy KochCalhoun | Calhoun '06 | State Qualifier | 2004 |
| 76 | 2:20.00 | Eleni GeorgatosDivision Avenue | Division Avenue | Section VIII State Qualifier | 2023 |
| 77 | 2:20.06 | Amanda SchmidtMassapequa | Massapequa '11 | Saint Anthony's Invitational | 2011 |
| 78 | 2:20.2 | Brittney CriscuoloEast Meadow | East Meadow '04 | Class A Counties | 2003 |
| 79 | 2:20.28 | Beatriz ChavarriaPort Washington | Port Washington '17 | Saint Anthony's Invitational | 2016 |
| 80 | 2:20.3 | Sana RaoofJericho | Jericho '08 | Division 3A Championships | 2006 |
| 81 | 2:20.35 | Joanna KenneyNorth Shore | North Shore '26 | Section 8 State Qualifer - Day 1 | 2026 |
| 82 | 2:20.4 | Marie LaMaidaHerricks | Herricks '05 | State Qualifier | 2003 |
| 83 | 2:20.4 | Kerryann BrankerIsland Trees | Island Trees '02 | State Qualifier | 2002 |
| 84 | 2:20.5 | Colleen AldrichWantagh | Wantagh '07 | State Qualifier | 2003 |
| 85 | 2:20.5 | Linda BradyEast Meadow | East Meadow '05 | Class AAA County | 2005 |
| 86 | 2:20.55 | Madeline BushNorth Shore | North Shore '23 | Section VIII State Qualifier | 2023 |
| 87 | 2:20.59 | Jenna DeAngeloGarden City | Garden City '12 | Saint Anthony's Invitational | 2009 |
| 88 | 2:20.61 | Kelsey MalmquistKellenberg | Kellenberg '06 | NSCHSAA League Championships | 2005 |
| 89 | 2:20.64 | Angelina WidmerGeneral Douglas MacArthur | General Douglas MacArthur '25 | Section 8 Class AAA | 2024 |
| 90 | 2:20.69 | Emily MoehringerMepham | Mepham '21 | Section VIII County Class 3A - Girls | |
| 91 | 2:20.69 | Lauren GruberSyosset | Syosset '16 | Section VIII Class County Championships | 2014 |
| 92 | 2:20.69 | Nataisha PlessFreeport | Freeport '07 | Saint Anthony’s Invitational | |
| 93 | 2:20.8 | Lauren GengoLong Beach | Long Beach '02 | State Qualifier | 2002 |
| 94 | 2:20.83 | Maria KoganPort Washington | Port Washington '17 | Saint Anthony's Invitational | 2016 |
| 95 | 2:20.89 | Maureen Ann LewinKellenberg | Kellenberg '19 | North Shore Invitational | 2017 |
| 96 | 2:20.9 | Ashlea McLaughlinUniondale | Uniondale '07 | Class AAA County | 2005 |
| 97 | 2:20.97 | Alyssa RotondoMacArthur | MacArthur '22 | Section VIII State Qualifier | 2022 |
| 98 | 2:20.98 | Nicolette AgostinaMacArthur | MacArthur '16 | Section VIII State Qualifier Meet | 2015 |
| 99 | 2:21.07 | Stephanie BazanNorth Shore | North Shore '16 | Section VIII Class County Championships | 2014 |
| 100 | 2:21.2 | Maddie AdamsGarden City | Garden City '08 | Conference IIB | 2007 |
