| 1 | 49.85 | Jovanni ParkinsonFarmingdale | Farmingdale | St. John's University Bill Ward Invitational | 2017 |
| 2 | 50.06 | Felipe CustodioValley Stream Central | Valley Stream Central '15 | St. John's University Bill Ward Invitational | 2017 |
| 3 | 50.07 | Roshane WrightElmont | Elmont '13 | St Joeph College Men | |
| 4 | 52.00 | Dylan BestlerMineola | Mineola '14 | St Joseph's College Indoor Invitational | 2018 |
| 5 | 52.09 | Idowu BamisileFarmingdale | Farmingdale | Molloy College Indoor Invitational | 2015 |
| 6 | 52.44 | Sean GradyEast Meadow | East Meadow '12 | St. John's University Bill Ward Invitational | 2014 |
| 7 | 52.59 | Jordan BrownFreeport | Freeport '17 | St Joeph College Men | |
| 8 | 52.7 | Isaiah MaskBaldwin | Baldwin '08 | Crossover #3 | 2007 |
| 9 | 52.83 | Ralph GangiSacred Heart | Sacred Heart | St Joseph's College Indoor Invitational | 2015 |
| 10 | 52.89 | Luke PascaleRoslyn | Roslyn '13 | Molloy College Indoor Invitational | 2015 |
| 11 | 52.92 | Vasu JoshiWantagh | Wantagh '15 | St Joeph College Men | |
| 12 | 53.08 | Dean GaulKellenberg | Kellenberg '13 | East Coast Confrence Indoor Championships | 2014 |
| 13 | 53.09 | Thomas SlatteryChaminade | Chaminade '14 | Suffolk Officials Meet | 2013 |
| 14 | 53.1 | Alix LamarreMepham | Mepham '09 | Crossover 3 Conferences 1 | 2008 |
| 15 | 53.15 | Nicholas BelcastroFarmingdale | Farmingdale '13 | Suffolk Coaches Meet | 2011 |
| 16 | 53.20 | Dylan ZangrilloMacArthur | MacArthur '14 | Suffolk Officials Meet | 2013 |
| 17 | 53.40 | Kevin MillsChaminade | Chaminade '15 | Boys Freshmen - Sophomore Championships | 2013 |
| 18 | 53.52 | Christopher HoltHoly Trinity | Holy Trinity '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 19 | 53.73 | Yvans OscarSewanhaka | Sewanhaka '17 | St Joseph's College Indoor Invitational | 2018 |
| 20 | 54.06 | Franklin TurciosFarmingdale | Farmingdale '10 | St Joseph's College Indoor Invitational | 2016 |
| 21 | 54.1 | David FreimanNorth Shore | North Shore '06 | Crossover #3 | 2007 |
| 22 | 54.11 | Ethan SochinskyDivision Avenue | Division Avenue '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 23 | 54.23 | Denzel WrightFarmingdale | Farmingdale | St. John's University 14th Annual Bill Ward Invitational | 2018 |
| 24 | 54.30 | Dwight SmithHoly Trinity | Holy Trinity '13 | Saint Anthony's Boys Developmental Meet 1 | 2012 |
| 25 | 54.31 | Kenneth HourseyBaldwin | Baldwin '16 | St Joeph College Men | |
| 26 | 54.4 | Marco BertolottiPort Washington | Port Washington '10 | Crossover 3 Conferences 2 | 2008 |
| 27 | 54.40 | Dylan GordonChaminade | Chaminade '13 | Suffolk Officials Meet | 2013 |
| 28 | 54.43 | Akeem WattsFarmingdale | Farmingdale | St. John's University Indoor Track Meet | 2010 |
| 29 | 54.5 | Daniel GoldsteinCold Spring Harbor | Cold Spring Harbor '05 | Crossover Meet #5 | 2005 |
| 30 | 54.60 | Brendan SchroederKellenberg | Kellenberg '16 | St. John's University Bill Ward Invitational | 2016 |
| 31 | 54.6 | Thomas FranzinoValley Stream North | Valley Stream North '07 | Crossover #3 | 2007 |
| 32 | 54.6 | Travis KennedyLawrence | Lawrence '08 | Crossover #3 | 2007 |
| 33 | 54.71 | Bjorn BjornssonDivision Avenue | Division Avenue '14 | St. John's University Bill Ward Invitational | 2014 |
| 34 | 54.8 | Noel ArcherWestbury | Westbury '09 | Crossover #3 | 2007 |
| 35 | 54.8 | Charlie RobesonWestbury | Westbury '05 | Crossover #6 | 2004 |
| 36 | 54.86 | Quinten DistanteHoly Trinity | Holy Trinity '18 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 37 | 54.88 | Andrew SimonValley Stream Central | Valley Stream Central '13 | Molloy College Indoor Invitational | 2015 |
| 38 | 54.9 | Christopher SchmittJFK Bellmore | JFK Bellmore '07 | Crossover #6 | 2004 |
| 39 | 54.9 | Charle ParazzoCalhoun | Calhoun '08 | Crossover 3 Conferences 2 | 2008 |
| 40 | 54.93 | Dillon SchwartzChaminade | Chaminade '11 | Suffolk Coaches Meet | 2011 |
| 41 | 55.04 | Kinsey SheppardBaldwin | Baldwin '12 | Molloy College Indoor Invitational | 2014 |
| 42 | 55.1 | Wayne StewartWestbury | Westbury '10 | Crossover 3 Conferences 1 | 2008 |
| 43 | 55.1 | Charles WhiteGarden City | Garden City '08 | Crossover #6 | 2004 |
| 44 | 55.15 | Ajani KerrSewanhaka | Sewanhaka '13 | St Joeph College Men | |
| 45 | 55.2 | Nick BalsamoMepham | Mepham '08 | Crossover #3 | 2007 |
| 46 | 55.2 | Kieran WallisSouth Side | South Side '05 | Crossover Meet #5 | 2005 |
| 47 | 55.2 | Lavar NeroBaldwin | Baldwin '07 | Crossover #3 | 2007 |
| 48 | 55.3 | Frankie DioguardiMassapequa | Massapequa '08 | Crossover 3 Conferences 1 | 2008 |
| 49 | 55.4 | Chris ParkerMepham | Mepham '08 | Crossover 3 Conferences 1 | 2008 |
| 50 | 55.4 | Chris BauerNorth Shore | North Shore '05 | Crossover Meet #5 | 2005 |
| 51 | 55.4 | Guy JoesphWestbury | Westbury '05 | Crossover #6 | 2004 |
| 52 | 55.5 | Eric WongMassapequa | Massapequa '09 | Crossover 3 Conferences 1 | 2008 |
| 53 | 55.5 | Kevon CarterValley Stream Central | Valley Stream Central '08 | Crossover 3 Conferences 2 | 2008 |
| 54 | 55.5 | Devon KennediLawrence | Lawrence '05 | Crossover #6 | 2004 |
| 55 | 55.51 | Mathew SpinelliMassapequa | Massapequa '15 | Suffolk Coaches Meet | 2013 |
| 56 | 55.58 | Daquan GrantFarmingdale | Farmingdale | St. John's University Indoor Track Meet | 2010 |
| 57 | 55.6 | Michael ColucciOceanside | Oceanside '08 | Crossover #3 | 2007 |
| 58 | 55.6 | Walter MendozaRoslyn | Roslyn '10 | Crossover 3 Conferences 1 | 2008 |
| 59 | 55.64 | Frank DiStefanoPlainedge | Plainedge '11 | Molloy College Indoor Invitational | 2014 |
| 60 | 55.7 | Daniel SmithClarke | Clarke '06 | Crossover Meet #5 | 2005 |
| 61 | 55.7 | Terrence MittoWestbury | Westbury '08 | Crossover 3 Conferences 1 | 2008 |
| 62 | 55.77 | Aidan CampolettanoHoly Trinity | Holy Trinity '13 | Saint Anthony's Boys Developmental Meet 1 | 2012 |
| 63 | 55.9 | Edward PicciniOceanside | Oceanside '08 | Crossover #3 | 2007 |
| 64 | 55.96 | Joseph MusarraFarmingdale | Farmingdale '11 | Suffolk Coaches Meet | 2011 |
| 65 | 55.99 | Brendan MeyerHoly Trinity | Holy Trinity '13 | Saint Anthony's Boys Developmental Meet 1 | 2012 |
| 66 | 56.00 | Anthony BellacosaFarmingdale | Farmingdale '14 | Suffolk Coaches Meet | 2011 |
| 67 | 56.02 | Vincent CeratiChaminade | Chaminade '13 | Boys Freshmen - Sophomore Championships | 2011 |
| 68 | 56.2 | Victor ReyesFreeport | Freeport '09 | Crossover 3 Conferences 1 | 2008 |
| 69 | 56.2 | Will PredunCold Spring Harbor | Cold Spring Harbor '05 | Crossover Meet #5 | 2005 |
| 70 | 56.27 | Ben SanchezOceanside | Oceanside '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 71 | 56.3 | Joe SalamoneGlen Cove | Glen Cove '05 | Crossover Meet #5 | 2005 |
| 72 | 56.3 | Ricky DemirakosOceanside | Oceanside '05 | Crossover #6 | 2004 |
| 73 | 56.4 | Steven CareyValley Stream North | Valley Stream North '08 | Crossover 3 Conferences 2 | 2008 |
| 74 | 56.4 | Jeff DeitelFarmingdale | Farmingdale '05 | Crossover #6 | 2004 |
| 75 | 56.4 | Romel VanegasHempstead | Hempstead '06 | Crossover #6 | 2004 |
| 76 | 56.42 | Daniel GrahamHoly Trinity | Holy Trinity '15 | Saint Anthony's Boys Developmental Meet | 2013 |
| 77 | 56.44 | Joe TanseyHewlett | Hewlett '14 | Saint Anthony's Boys Developmental Meet | 2013 |
| 78 | 56.54 | Tyler TarnowskiSyosset | Syosset '15 | Suffolk Officials Meet | 2013 |
| 79 | 56.6 | Alan ArtiedaSouth Side | South Side '06 | Crossover Meet #5 | 2005 |
| 80 | 56.7 | Ryan MurphyCalhoun | Calhoun '08 | Crossover 3 Conferences 2 | 2008 |
| 81 | 56.7 | Carlo BalboValley Stream North | Valley Stream North '08 | Crossover #3 | 2007 |
| 82 | 56.7 | Eric FlorioWheatley | Wheatley '05 | Crossover Meet #5 | 2005 |
| 83 | 56.7 | Thomas McAvoyOceanside | Oceanside '07 | Crossover #6 | 2004 |
| 84 | 56.8 | Matthew StephensonJFK Bellmore | JFK Bellmore '09 | Crossover #3 | 2007 |
| 85 | 56.82 | Griffin KreitLynbrook | Lynbrook '14 | Saint Anthony's Boys Developmental Meet | 2013 |
| 86 | 56.87 | Kevin MartinezHewlett | Hewlett '14 | Saint Anthony's Boys Developmental Meet | 2013 |
| 87 | 56.9 | David MonteiroValley Stream North | Valley Stream North '08 | Crossover 3 Conferences 2 | 2008 |
| 88 | 56.9 | Frank LozadaValley Stream North | Valley Stream North '07 | Crossover #3 | 2007 |
| 89 | 56.94 | Christopher FigatOceanside | Oceanside '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 90 | 57.00 | Michael DioGuardiMassapequa | Massapequa '10 | St. John's University Indoor Track Meet | 2010 |
| 91 | 57.0 | Matthew MunroeValley Stream Central | Valley Stream Central '10 | Crossover 3 Conferences 2 | 2008 |
| 92 | 57.0 | Michael YangOceanside | Oceanside '09 | Crossover 3 Conferences 1 | 2008 |
| 93 | 57.1 | Vancardi FosterElmont | Elmont '05 | Crossover #6 | 2004 |
| 94 | 57.1 | Mahnee NahSyosset | Syosset '08 | Crossover #3 | 2007 |
| 95 | 57.1 | Chris BarbarelloMassapequa | Massapequa '05 | Crossover #6 | 2004 |
| 96 | 57.1 | Jon CastaldoValley Stream Central | Valley Stream Central '05 | Crossover #6 | 2004 |
| 97 | 57.2 | David ColettaSouth Side | South Side '09 | Crossover 3 Conferences 1 | 2008 |
| 98 | 57.21 | Daniel BrennanKellenberg | Kellenberg '09 | St. John's University Indoor Track Meet | 2010 |
| 99 | 57.22 | John DignamChaminade | Chaminade '18 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 100 | 57.53 | Brendan MorrisonChaminade | Chaminade '14 | Saint Anthony's Boys Developmental Meet | 2013 |
