| 1 | 4:38.22 | Lily StrebelWesthampton Beach | Westhampton Beach '25 | Section 11 State Quals | 2024 |
| 2 | 4:39.23 | Cali GabrielsonMt. Sinai | Mt. Sinai '28 | Section XI Girls Zeitler Coaches Classic | 2026 |
| 3 | 4:41.50 | Roshni SinghBay Shore | Bay Shore '20 | Section XI Indoor State Qualifier Meet | 2019 |
| 4 | 4:43.16 | Alexandra HaysShoreham-Wading River | Shoreham-Wading River '17 | Section XI Indoor State Qualifier Meet | 2017 |
| 5 | 4:44.75 | Klaire KlemensWest Islip | West Islip '18 | Section XI Indoor State Qualifier Meet | 2017 |
| 6 | 4:45.11 | Noreen GuilfoyleMount Sinai | Mount Sinai '18 | Section XI Indoor State Qualifier Meet | 2017 |
| 7 | 4:46.60 | Sierra KoehlerWest Islip | West Islip '17 | Section XI Indoor State Qualifier Meet | 2017 |
| 8 | 4:46.80 | Kayla ForschNorthport | Northport '26 | GIRLS League Championships 2 | 2025 |
| 9 | 4:48.02 | Gabby SchneiderSmithtown East | Smithtown East '19 | Long Island Elite Track Invitational | 2018 |
| 10 | 4:48.32 | Jaclyn GallerySmithtown East | Smithtown East '17 | Section XI Large School Championships | 2014 |
| 11 | 4:49.14 | Taylor TotevskiSayville | Sayville '23 | Section XI Girls Small SchooolChampionships | 2020 |
| 12 | 4:49.51 | Molly RamirezSachem North | Sachem North '20 | Section XI Indoor State Qualifier Meet | 2017 |
| 13 | 4:49.61 | Marcie HoganEastport-South Manor | Eastport-South Manor '19 | Section XI Indoor State Qualifier Meet | 2019 |
| 14 | 4:50.13 | Briana GrantWard Melville | Ward Melville '21 | Section XI Girls Indoor League Championships | 2019 |
| 15 | 4:50.57 | Elise RamirezSachem North | Sachem North '15 | Section XI Indoor State Qualifier Meet | 2015 |
| 16 | 4:50.66 | Rachel RuggieroSachem East | Sachem East '18 | Section XI Indoor State Qualifier Meet | 2017 |
| 17 | 4:50.71 | Amanda DwyerShoreham-Wading River | Shoreham-Wading River '17 | Section XII Small School Championships | 2017 |
| 18 | 4:50.96 | Danelle RoseMiller Place | Miller Place '20 | Section XI Indoor State Qualifier Meet | 2019 |
| 19 | 4:51.04 | Christina DuffySayville | Sayville '29 | Section XI Girls Small School County Championships | 2026 |
| 20 | 4:51.37 | Nicole BrievaKings Park | Kings Park '12 | Girls Section XI 2008 League Championships | |
| 21 | 4:51.54 | Christina YakaboskiRiverhead | Riverhead '20 | Section XI Indoor State Qualifier Meet | 2020 |
| 22 | 4:51.84 | Jenna NewmanSayville | Sayville '19 | Jim Howard Meet - Small Schools | 2019 |
| 23 | 4:52.94 | Fiona McLoughlinCommack | Commack '20 | Section XI Girls Crossover D | 2018 |
| 24 | 4:53.66 | Christina YakabosRiverhead | Riverhead '20 | Long Island Elite Track Invitational | 2019 |
| 25 | 4:54.32 | Sarah WisnieskiSmithtown East | Smithtown East '25 | Section 11 State Quals | 2024 |
| 26 | 4:54.39 | Kate CochranWard Melville | Ward Melville '19 | Section XI Indoor State Qualifier Meet | 2017 |
| 27 | 4:54.51 | Adriana RoaSachem East | Sachem East '25 | GIRLS Large Schools Championships | 2025 |
| 28 | 4:54.78 | Allison StapletonCommack | Commack '11 | Art Mitchell Memorial Meet | 2011 |
| 29 | 4:54.99 | Stephanie BarnesBay Shore | Bay Shore '09 | Girls Section XI 2008 League Championships | |
| 30 | 4:55.68 | Gianna MinconeSt. Anthony's | St. Anthony's '16 | NSCHSAA Indoor League Championships | 2014 |
| 31 | 4:55.90 | Jennifer FurmanSt. Anthony's | St. Anthony's '19 | NSCHSAA Indoor League Championships | 2017 |
| 32 | 4:55.98 | DeCicco AlexandraEastport-South Manor | Eastport-South Manor '16 | Section XI Girls Indoor League Championships | 2013 |
| 33 | 4:56.44 | Alexandra SmithShoreham-Wading River | Shoreham-Wading River '19 | Art Mitchell Class Meet - Small Schools | 2019 |
| 34 | 4:56.46 | Grace WeigeleWalt Whitman | Walt Whitman '21 | Jim Howard Meet - Large ols | 2020 |
| 35 | 4:56.46 | Nolan LauraMiller Place | Miller Place '16 | Girls Crossover Meet D | 2014 |
| 36 | 4:57.18 | Danielle TorittoSmithtown East | Smithtown East '09 | Art Mitchell Memorial Meet | 2008 |
| 37 | 4:57.18 | Jackie AmatoWesthampton Beach | Westhampton Beach '21 | Section XI Girls Crossover B | 2018 |
| 38 | 4:57.18 | Maggie RossBayport-Blue Point | Bayport-Blue Point '18 | Long Island Elite Track Invitational | 2018 |
| 39 | 4:57.47 | Caitlyn RyanSachem East | Sachem East '10 | Girls Large School Championships | 2009 |
| 40 | 4:57.53 | Laurie SemetsisSachem East | Sachem East '13 | Section XI Large School Championships | 2012 |
| 41 | 4:57.72 | Brooke JohnsonShoreham-Wading River | Shoreham-Wading River '09 | Girls Indoor Large and Small Championships 2007 | 2007 |
| 42 | 4:57.86 | Josephine CritchlWest Babylon | West Babylon '21 | Long Island Elite Track Invitational | 2018 |
| 43 | 4:58.88 | Mariah Jno-CharlesBellport | Bellport '15 | Art Mitchell Class Meet | 2015 |
| 44 | 4:58.96 | Isabella HornWard Melville | Ward Melville | Section XI Girls League 2 Championship | 2026 |
| 45 | 4:59.00 | Victoria LaguerreWard Melville | Ward Melville '22 | Jim Howard Meet - Large Schools | 2019 |
| 46 | 4:59.05 | Elizabeth FierroNorthport | Northport '11 | Jim Howard Meet | 2009 |
| 47 | 4:59.12 | Hailey MarcelloSt. John the Baptist | St. John the Baptist '19 | Long Island Elite Track Invitational | 2018 |
| 48 | 4:59.14 | Rebecca ClackettHauppauge | Hauppauge '20 | Section XI Girls Crossover B | 2019 |
| 49 | 4:59.17 | Emily GintySmithtown East | Smithtown East '20 | Long Island Elite Track Invitational | 2018 |
| 50 | 4:59.46 | Emma BoyleHuntington | Huntington '26 | Section XI Girls Crossover C (S1, S2) | 2025 |
| 51 | 4:59.75 | Ava VaccarellaMattituck | Mattituck '23 | Jim Howard Meet - Small Schools | 2019 |
| 52 | 4:59.81 | Kate KeaginsBay Shore | Bay Shore '08 | Girls Indoor Large and Small Championships 2007 | 2007 |
| 53 | 4:59.91 | Fina DiBiasoWesthampton Beach | Westhampton Beach '28 | GIRLS League Championships 4 | 2025 |
| 54 | 4:59.94 | Lauren TrejoSachem East | Sachem East '21 | Section XI Girls Indoor League Championships | 2020 |
| 55 | 4:59.95 | Erin MaudPatchogue-Medford | Patchogue-Medford '15 | Jim Howard Meet | 2015 |
| 56 | 4:59.97 | Marianna DuffySayville | Sayville '27 | GIRLS League Championships 4 | 2025 |
| 57 | 4:59.99 | Cecile ReugeWard Melville | Ward Melville '08 | Girls Indoor Large and Small Championships 2007 | 2007 |
| 58 | 5:00.20 | Dana CebulskiEast Hampton | East Hampton '15 | Jim Howard Meet | 2013 |
| 59 | 5:00.58 | Molly DearieWard Melville | Ward Melville '15 | Section XI Girls Indoor League Championships | 2015 |
| 60 | 5:00.65 | Sierra GrayMiller Place | Miller Place '22 | Section XI Girls Small SchooolChampionships | 2020 |
| 61 | 5:00.74 | Claire RonanComsewogue | Comsewogue '21 | Section XI Girls Crossover D | 2020 |
| 62 | 5:00.83 | Bridget AbraldesSachem East | Sachem East '20 | Long Island Elite Track Invitational | 2018 |
| 63 | 5:01.06 | Ava EngstromEast Hampton | East Hampton '21 | Jim Howard Meet - Small Schools | 2019 |
| 64 | 5:01.10 | Penelope GreeneEast Hampton | East Hampton '21 | Section XI Girls Small SchooolChampionships | 2020 |
| 65 | 5:01.17 | Allison CreightonMiller Place | Miller Place '27 | Section XI Girls League 5 Championship | 2026 |
| 66 | 5:01.21 | Gabrielle SchneiderSmithtown East | Smithtown East '19 | Section XI Girls Crossover B | 2016 |
| 67 | 5:01.24 | Gianna CostelloNorthport | Northport | Section XI State Qualifer Meet Day 2 | 2026 |
| 68 | 5:01.56 | Isabella DiPalermMount Sinai | Mount Sinai '20 | Girls Crossover Meet D | 2018 |
| 69 | 5:01.66 | Samantha D'AmatoNorthport | Northport '10 | Girls Section XI 2008 League Championships | |
| 70 | 5:01.69 | Veronica LeddySt. Anthony's | St. Anthony's '12 | NSCHSAA Christmas Classic | 2008 |
| 71 | 5:01.73 | Alyssa DorneySt. John the Baptist | St. John the Baptist '11 | 2009 NSCHSAA Christmas Classic | 2009 |
| 72 | 5:02.12 | Megan LankowiczSayville | Sayville '26 | GIRLS League Championships 4 | 2025 |
| 73 | 5:02.29 | Corinne WeldonWilliam Floyd | William Floyd '10 | Girls Large School Championships | 2009 |
| 74 | 5:02.44 | Megan KielbasaRiverhead | Riverhead '20 | Section XI Girls Crossover B | 2019 |
| 75 | 5:02.89 | Katie IoccaConnetquot | Connetquot '20 | Section XI Girls Indoor League Championships | 2017 |
| 76 | 5:03.43 | Victoria CiottiSt. Anthony's | St. Anthony's '12 | Long Island Elite Track Invitational | 2011 |
| 77 | 5:03.43 | Bridget RoellKings Park | Kings Park '20 | Section XI Small School Championships | 2018 |
| 78 | 5:03.44 | Serefina DiBiasoWesthampton Beach | Westhampton Beach | Section XI State Qualifier Meet (Day 1) | 2025 |
| 79 | 5:03.50 | Leeanna SimoBayport-Blue Point | Bayport-Blue Point '08 | Girls Crossover b4 | 2006 |
| 80 | 5:03.56 | Veronica SzygalowLindenhurst | Lindenhurst '20 | Section XI Girls Indoor League Championships | 2020 |
| 81 | 5:04.14 | Emily CerritoNorthport | Northport '17 | Girls Crossover Meet D | 2015 |
| 82 | 5:04.29 | Anya SchmidtEast Islip | East Islip '16 | Jim Howard Meet | 2016 |
| 83 | 5:04.52 | Alex TaylorKings Park | Kings Park '10 | Art Mitchell Memorial Meet | 2008 |
| 84 | 5:04.54 | Joy PetersenEast Islip | East Islip '22 | Section XI Girls Indoor League Championships | 2020 |
| 85 | 5:04.60 | Amanda FilibertoNorthport | Northport '07 | Girls Crossover b4 | 2006 |
| 86 | 5:04.62 | Lauren CaseyWard Melville | Ward Melville | Section XI Girls Zeitler Coaches Classic | 2026 |
| 87 | 5:04.81 | Meagan DonovanJohn Glenn | John Glenn '10 | Art Mitchell Memorial Meet | 2008 |
| 88 | 5:04.92 | Samantha SchnellPort Jefferson | Port Jefferson '16 | Girls Crossover Meet B | 2014 |
| 89 | 5:04.98 | Nicole AbbondandeHuntington | Huntington '18 | Section XI Girls Crossover A | 2017 |
| 90 | 5:05.00 | Katie MarshallKings Park | Kings Park '08 | Girls Crossover C2 | 2006 |
| 91 | 5:05.03 | Gianna RinaldiCommack | Commack '19 | Section XI Girls Crossover D | 2018 |
| 92 | 5:05.06 | Katie HempflingSachem East | Sachem East '14 | Section XI Girls Indoor League Championships | 2014 |
| 93 | 5:05.30 | Karli MurphySachem East | Sachem East '16 | Long Island Elite Track Invitational | 2013 |
| 94 | 5:05.35 | Veronica SzygalowiczLindenhurst | Lindenhurst '20 | Section XI Girls Crossover D | 2020 |
| 95 | 5:05.47 | Marissa CossaroNorthport | Northport '13 | Section XI Girls Indoor League Championships | 2013 |
| 96 | 5:05.60 | Rose HayesWesthampton Beach | Westhampton Beach '22 | Section XI Girls Crossover B | 2019 |
| 97 | 5:05.85 | Dana BegginsWest Babylon | West Babylon '17 | Section XI Girls Crossover B | 2016 |
| 98 | 5:05.95 | Hannah HellerWest Babylon | West Babylon '19 | Section XI Girls Crossover B | 2018 |
| 99 | 5:05.98 | Sarah ZieveNorthport | Northport '13 | Girls Crossover Meet A | 2012 |
| 100 | 5:06.31 | Grace HeilHarborfields | Harborfields '20 | Section XI Girls Indoor League Championships | 2017 |
