| 1 | 5:12.55 | Annie KeownStony Brook | Stony Brook | St. John's University Indoor Invitational | 2012 |
| 2 | 5:12.66 | Lorraine McCarthyStony Brook | Stony Brook | St. John's University Indoor Invitational | 2012 |
| 3 | 5:32.65 | Kelly ParkerSt. Anthony's | St. Anthony's '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 4 | 5:34.27 | Madeline BargetConnetquot | Connetquot '22 | Saint Anthony's Developmental Meet 2 | 2019 |
| 5 | 5:35.34 | Kaitlyn IoccaConnetquot | Connetquot '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 6 | 5:36.37 | Erin MacDonellSayville | Sayville '14 | St. John's University Bill Ward Invitational | 2017 |
| 7 | 5:37.18 | Germaine HarbaughMiller Place | Miller Place '17 | St. John's University Bill Ward Invitational | 2017 |
| 8 | 5:37.27 | Gina D'AngeloSt. Anthony's | St. Anthony's '14 | Saint Anthony's Girls Developmental Meet | 2013 |
| 9 | 5:38.97 | Nicole FergusonWilliam Floyd | William Floyd '16 | St. John's University Bill Ward Invitational | 2017 |
| 10 | 5:39.05 | Erin LettieriWest Islip | West Islip '16 | St Joseph's College Indoor Invitational | 2018 |
| 11 | 5:39.44 | Madison IsnardiSt. John the Baptist | St. John the Baptist '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 12 | 5:39.96 | Brittany WardNorth Babylon | North Babylon '12 | East Coast Confrence Indoor Championships | 2014 |
| 13 | 5:40.19 | Penelope GreeneEast Hampton | East Hampton '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 14 | 5:42.05 | Caelan SchretzmayerPort Jefferson | Port Jefferson '22 | Saint Anthony's Developmental Meet 2 | 2019 |
| 15 | 5:42.32 | Kerri McCormackSt. John the Baptist | St. John the Baptist '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 16 | 5:43.73 | Larisa DorrianSt. Anthony's | St. Anthony's '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 17 | 5:45.95 | Brooke CatalanoWest Islip | West Islip '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 18 | 5:47.18 | Meagan HavilandRocky Point | Rocky Point '17 | St Joseph's College Indoor Invitational | 2018 |
| 19 | 5:47.59 | Shea BohanSt. Anthony's | St. Anthony's '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 20 | 5:50.52 | Karli MurphySachem East | Sachem East '16 | St Joseph's College Indoor Invitational | 2018 |
| 21 | 5:50.80 | Gwen CorleySt. Anthony's | St. Anthony's '03 | Friendship Games Championship | 2002 |
| 22 | 5:51.08 | Jacqueline AndersoBay Shore | Bay Shore '14 | St. John's University Bill Ward Invitational | 2014 |
| 23 | 5:51.32 | Brianna DelaCruzLindenhurst | Lindenhurst | St Joseph's College Indoor Invitational | 2018 |
| 24 | 5:53.09 | Erin MaudPatchogue-Medford | Patchogue-Medford '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 25 | 5:53.25 | Jenna PearsallEast Islip | East Islip '10 | St. John's University Bill Ward Invitational | 2013 |
| 26 | 5:53.71 | Ava EngstromEast Hampton | East Hampton '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 27 | 5:55.03 | Samantha MauriceSachem East | Sachem East '12 | St. John's University Bill Ward Invitational | 2013 |
| 28 | 5:55.19 | Krista O'ConnorWest Islip | West Islip '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 29 | 5:55.37 | Kristina SchrepfSachem North | Sachem North '13 | St. John's University Bill Ward Invitational | 2013 |
| 30 | 5:55.59 | Sabrina SpeziaSt. John the Baptist | St. John the Baptist '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 31 | 5:56.28 | Nicole FranzWalt Whitman | Walt Whitman '14 | St Joseph's College Indoor Invitational | 2016 |
| 32 | 5:56.90 | Margaret PappasSt. John the Baptist | St. John the Baptist '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 33 | 5:58.18 | Megan LaveryIslip | Islip '11 | Molloy College Indoor Invitational | 2014 |
| 34 | 5:58.24 | Katie MichtaSachem North | Sachem North '14 | St. John's University Bill Ward Invitational | 2017 |
| 35 | 5:58.93 | Cassidy JacobusWard Melville | Ward Melville '17 | St. John's University 14th Annual Bill Ward Invitational | 2018 |
| 36 | 5:59.07 | Diana MonacoCenter Moriches | Center Moriches '15 | St. John's University Bill Ward Invitational | 2017 |
| 37 | 6:01.09 | Amanda TascarellaRocky Point | Rocky Point '14 | Saint Anthony's Girls Developmental Meet | 2013 |
| 38 | 6:02.31 | Lindsey SchwasnicSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 39 | 6:03.10 | Lauren GilbrideSt. Anthony's | St. Anthony's '03 | Friendship Games 1 | 2001 |
| 40 | 6:04.04 | Georgie NicholesCenter Moriches | Center Moriches '14 | St. John's University Bill Ward Invitational | 2015 |
| 41 | 6:06.10 | Kathleen MartinSt. Anthony's | St. Anthony's '04 | Friendship Games 1 | 2001 |
| 42 | 6:08.16 | Amanda SpragueConnetquot | Connetquot '14 | St. John's University Bill Ward Invitational | 2017 |
| 43 | 6:10.14 | Jessica FriedmanRocky Point | Rocky Point '17 | St Joseph's College Indoor Invitational | 2018 |
| 44 | 6:10.33 | Cassandra CostarelliRocky Point | Rocky Point '13 | St. John's University Bill Ward Invitational | 2013 |
| 45 | 6:10.57 | Samantha PapadopoulosSmithtown West | Smithtown West '17 | St Joseph's College Indoor Invitational | 2018 |
| 46 | 6:10.75 | Carly DebonoPatchogue-Medford | Patchogue-Medford '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 47 | 6:14.63 | Maria MolnarSt. Anthony's | St. Anthony's '15 | St. John's University Bill Ward Invitational | 2017 |
| 48 | 6:14.82 | Shelbi WussWalt Whitman | Walt Whitman '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 49 | 6:15.19 | Alicia ShipseyLindenhurst | Lindenhurst '16 | St Joseph's College Indoor Invitational | 2018 |
| 50 | 6:17.94 | Bianca DeluciaPatchogue-Medford | Patchogue-Medford '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 51 | 6:18.13 | Jillian IsolanoWest Islip | West Islip '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 52 | 6:19.69 | Jennifer O'ConnorLongwood | Longwood '16 | St Joseph's College Indoor Invitational | 2018 |
| 53 | 6:19.73 | Brianna LawrencePatchogue-Medford | Patchogue-Medford '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 54 | 6:19.97 | Abigail LehrCenter Moriches | Center Moriches '15 | St Joseph's College Indoor Invitational | 2016 |
| 55 | 6:24.00 | Amanda IasparoWest Islip | West Islip '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 56 | 6:24.86 | Julia BorisSachem North | Sachem North '18 | St. John's University 14th Annual Bill Ward Invitational | 2018 |
| 57 | 6:24.95 | Erica BavaroWest Islip | West Islip '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 58 | 6:26.35 | Hannah MartinPatchogue-Medford | Patchogue-Medford '18 | Saint Anthony's Girls Developmental Meet | 2013 |
| 59 | 6:26.58 | Colleen RadiganSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 60 | 6:27.70 | Taylor VerdiSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 61 | 6:28.19 | Tierney RuppelLindenhurst | Lindenhurst '15 | St. John's University Bill Ward Invitational | 2015 |
| 62 | 6:30.37 | Theresa DefillippoPatchogue-Medford | Patchogue-Medford '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 63 | 6:30.41 | Kelly RobertsWard Melville | Ward Melville '13 | St. John's University Bill Ward Invitational | 2013 |
| 64 | 6:30.49 | Karly McGeeConnetquot | Connetquot '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 65 | 6:32.84 | Sarah DernMercy | Mercy '18 | St. John's University 14th Annual Bill Ward Invitational | 2018 |
| 66 | 6:34.25 | Daniela PinzonBay Shore | Bay Shore '16 | St Joseph's College Indoor Invitational | 2018 |
| 67 | 6:36.44 | Alexis ParesSt. Anthony's | St. Anthony's '20 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 68 | 6:36.98 | Monica GrismerSachem North | Sachem North '15 | St. John's University Bill Ward Invitational | 2015 |
| 69 | 6:39.60 | Alex BergenSachem East | Sachem East '16 | St Joseph's College Indoor Invitational | 2018 |
| 70 | 6:44.04 | Alana ConstantiniRocky Point | Rocky Point '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 71 | 6:45.04 | Shannon DowdShoreham-Wading River | Shoreham-Wading River '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 72 | 6:45.69 | Ashley EckhoffSt. Anthony's | St. Anthony's '20 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 73 | 6:45.74 | Jenna MercurioWest Islip | West Islip '14 | Saint Anthony's Girls Developmental Meet | 2013 |
| 74 | 6:48.38 | Kerri ConteSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 75 | 7:11.69 | Victoria QuinonesConnetquot | Connetquot '16 | St Joseph's College Indoor Invitational | 2018 |
| 76 | 7:11.72 | Monica RodriguezEastport-South Manor | Eastport-South Manor '19 | St. John's University 14th Annual Bill Ward Invitational | 2018 |
| 77 | 7:12.72 | Mia AmatoSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 78 | 7:21.68 | Rudiana AngladeNorth Babylon | North Babylon '14 | St. John's University Bill Ward Invitational | 2017 |
| 79 | 7:39.54 | Christina ParrishMount Sinai | Mount Sinai '14 | St. John's University Bill Ward Invitational | 2014 |
| 80 | 7:45.52 | Lauren DooleySt. Anthony's | St. Anthony's '18 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 81 | 7:46.66 | Isabelle Revere-BSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 82 | 7:49.54 | Christiana MaceluSt. Anthony's | St. Anthony's '20 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 83 | 8:17.98 | Samantha EdnieSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 84 | 8:32.05 | Kaithlyn HendrickSt. Anthony's | St. Anthony's '20 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 85 | 9:13.19 | Ivana TelesmanicSt. Anthony's | St. Anthony's '19 | Saint Anthony's Boys - Girls Developmental | 2018 |
