| 1 | 1:01.36 | Cassie GibbonsBrentwood | Brentwood '14 | St Joseph's College Indoor Invitational | 2018 |
| 2 | 1:01.89 | Nicole ElardeCommack | Commack '13 | Molloy College Indoor Invitational | 2014 |
| 3 | 1:02.52 | Essence RogersBay Shore | Bay Shore '11 | St. John's University Indoor Invitational | 2012 |
| 4 | 1:02.69 | Melissa CunningghSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 5 | 1:02.96 | Kathryn ManziStony Brook | Stony Brook | St. John's University Indoor Invitational | 2012 |
| 6 | 1:03.08 | Melissa CunninghaSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 7 | 1:06.01 | Dresilla GrierStony Brook | Stony Brook | St. John's University Indoor Invitational | 2012 |
| 8 | 1:06.11 | Catherine SandkuhlNorth Babylon | North Babylon '11 | St. John's University Bill Ward Invitational | 2013 |
| 9 | 1:06.54 | Jessica DoddoWalt Whitman | Walt Whitman '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 10 | 1:06.56 | Shannon BoyleSt. Anthony's | St. Anthony's '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 11 | 1:06.83 | Audrey JosephConnetquot | Connetquot '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 12 | 1:06.84 | Courtney PabstBellport | Bellport '15 | Saint Anthony's Girls Developmental Meet | 2013 |
| 13 | 1:07.18 | Alexandra EyeSt. John the Baptist | St. John the Baptist '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 14 | 1:07.66 | Sarah DolphinSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 15 | 1:07.84 | Leanna YatesCentral Islip | Central Islip '23 | Saint Anthony's Developmental Meet 2 | 2019 |
| 16 | 1:08.29 | Ashley FaulhaberRocky Point | Rocky Point '14 | Saint Anthony's Girls Developmental Meet | 2013 |
| 17 | 1:08.37 | Ava BiancardiSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 18 | 1:09.33 | Jaclyn LouroSt. Anthony's | St. Anthony's '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 19 | 1:09.53 | Haley GibbonsBellport | Bellport '14 | Saint Anthony's Girls Developmental Meet | 2013 |
| 20 | 1:09.70 | Olivia AmbergerConnetquot | Connetquot '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 21 | 1:10.12 | Bianca DeluciaPatchogue-Medford | Patchogue-Medford '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 22 | 1:10.31 | Alexa NuzziSachem North | Sachem North '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 23 | 1:10.38 | Emily FarrellSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 24 | 1:10.55 | Kelsey KrupskiWest Islip | West Islip '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 25 | 1:10.91 | Grace BlombergShoreham-Wading River | Shoreham-Wading River '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 26 | 1:11.12 | Lauren HoffmanWalt Whitman | Walt Whitman '14 | St. John's University Bill Ward Invitational | 2014 |
| 27 | 1:11.21 | Allison GrajalesSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 28 | 1:11.57 | Casey DuganPatchogue-Medford | Patchogue-Medford '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 29 | 1:12.07 | Rhianna CongerLindenhurst | Lindenhurst '10 | Molloy College Indoor Invitational | 2014 |
| 30 | 1:12.09 | Laila GedeonSt. John the Baptist | St. John the Baptist '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 31 | 1:12.25 | Ava RussellSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 32 | 1:12.44 | Gabrielle JeanSt. John the Baptist | St. John the Baptist '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 33 | 1:13.50 | Jessica FriedmanRocky Point | Rocky Point '17 | St. John's University Bill Ward Invitational | 2017 |
| 34 | 1:13.54 | Emily StamSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 35 | 1:14.25 | Katie MichtaSachem North | Sachem North '14 | St. John's University Bill Ward Invitational | 2017 |
| 36 | 1:15.13 | Diana MonacoCenter Moriches | Center Moriches '15 | St. John's University Bill Ward Invitational | 2017 |
| 37 | 1:16.71 | Maria MolnarSt. Anthony's | St. Anthony's '15 | St. John's University Bill Ward Invitational | 2017 |
| 38 | 1:16.97 | Kelsey JordanWesthampton Beach | Westhampton Beach '17 | St Joseph's College Indoor Invitational | 2018 |
| 39 | 1:18.89 | Aleekay WarrenWalter G. O'Connell-Copiague | Walter G. O'Connell-Copiague | USATF Long Island Open & Masters Indoor Track & Field Championships | 2024 |
| 40 | 1:20.15 | Jennica JosemaPatchogue-Medford | Patchogue-Medford '10 | St. John's University Indoor Invitational | 2012 |
| 41 | 1:25.35 | Julia IannoSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2017 |
| 42 | 1:28.71 | Kaia OcampoIslip | Islip '31 | USATF Long Island Youth Indoor Track & Field Championships | 2024 |
| 43 | 1:29.25 | Alessandra PavlovicHauppauge | Hauppauge '31 | USATF Long Island Youth Indoor Track & Field/Para-Athletic Championships | 2025 |
| 44 | 2:18.32 | Lane 5Eastport-South Manor | Eastport-South Manor | USATF Long Island Youth Indoor Track & Field Championships | 2024 |
