| 1 | 21.32 | Joshua BuckleyAcademy Charter (Sec 8.) | Academy Charter (Sec 8.) '28 | Section 8 AA County Championship | 2026 |
| 2 | 21.43 | Aidan PeterkinElmont Memorial | Elmont Memorial '26 | Section 8 AA County Championship | 2026 |
| 3 | 21.48 | Leroy BarrettRoosevelt | Roosevelt '26 | Paul Limmer Invitational | 2026 |
| 4 | 21.50 | Jovanni ParkinsonFarmingdale | Farmingdale | Stony Brook University - Wolfie Invitational | 2016 |
| 5 | 21.6 | Windell WallaceLawrence | Lawrence '07 | State Qualifier | 2007 |
| 6 | 21.6 | Atiba LiverpoolElmont | Elmont '05 | Division IIA | 2005 |
| 7 | 21.7 | Nicholas GuscottBaldwin | Baldwin '08 | Class AAA County | 2008 |
| 8 | 21.8 | Paul TimotheElmont | Elmont '08 | Division 2A Championships | |
| 9 | 21.8 | Onix SalvaMalverne | Malverne '02 | State Qualifier | 2002 |
| 10 | 21.85 | Jacob ButlerLong Island Lutheran | Long Island Lutheran | North Shore Invitational | 2025 |
| 11 | 21.87 | Raymond JonesRoosevelt | Roosevelt '14 | New York State Track & Field Championships | 2014 |
| 12 | 21.88 | Giordano WilliamsUniondale | Uniondale '19 | Knight Time Invitational | 2018 |
| 13 | 21.89 | Shaka ShomariHoly Trinity | Holy Trinity '15 | NSCHSAA League Championships | 2015 |
| 14 | 21.89 | Demoni GilkesElmont | Elmont '18 | Knight Time Invitational | 2018 |
| 15 | 21.9 | Joseph ScherH. Frank Carey | H. Frank Carey '08 | Division 2A Championships | 2006 |
| 16 | 21.90 | Charles GilreathHoly Trinity | Holy Trinity '09 | Post Easter Classic | 2009 |
| 17 | 21.9 | Damian SamuelUniondale | Uniondale '06 | Class AA Championships | 2006 |
| 18 | 21.9 | Dale McdonaldRoosevelt | Roosevelt '10 | 2009 Nassau Coaches Invitational - Boys | |
| 19 | 21.9 | James ClarkeWestbury | Westbury '03 | Class B County | 2002 |
| 20 | 21.9 | Michael WrightUniondale | Uniondale '05 | Division IA Championships | 2005 |
| 21 | 21.9 | Drew HarrisonWestbury | Westbury '04 | Division IIB | 2002 |
| 22 | 21.9 | Clark HindsFloral Park Memorial | Floral Park Memorial '08 | Class AA County | 2008 |
| 23 | 21.92 | Darnelle MickensWestbury | Westbury '10 | Saint Anthony's Invitational | 2010 |
| 24 | 21.96 | Ethan HindsVal Stream South | Val Stream South '26 | The Seahawk Invitational | 2026 |
| 25 | 21.97 | Christopher DeanOyster Bay | Oyster Bay | Section 8 Class A | 2024 |
| 26 | 22.0 | Terrence ShawValley Stream Central | Valley Stream Central '07 | Division 2A Championships | 2006 |
| 27 | 22.0 | Marc MauroLocust Valley | Locust Valley '10 | 2009 Nassau Coaches Invitational - Boys | |
| 28 | 22.00 | D'Monte WoodyFreeport | Freeport '15 | Knight Time Invitational | 2015 |
| 29 | 22.0 | Jermaine ArtwellUniondale | Uniondale '04 | State Qualifier | 2004 |
| 30 | 22.0 | Elvis LewisWest Hempstead | West Hempstead '05 | State Qualifier | 2004 |
| 31 | 22.01 | Thomas SmallFloral Park Memorial | Floral Park Memorial | Section VIII State Qualifier Day 2 | 2025 |
| 32 | 22.01 | Kazeem ScottFreeport | Freeport | Section VIII State Qualifier | 2023 |
| 33 | 22.01 | Okikijesu FashakinAcademy Charter (Sec 8.) | Academy Charter (Sec 8.) '26 | Section 8 AA County Championship | 2026 |
| 34 | 22.07 | Nigel WrightBaldwin | Baldwin | Blue and White Invitational | 2025 |
| 35 | 22.08 | Josiah BrownHoly Trinity | Holy Trinity '24 | The Nassau Coaches Invitational | 2022 |
| 36 | 22.09 | Felipe CustodioValley Stream Central | Valley Stream Central '15 | Section VIII Class 3A County Championships | 2015 |
| 37 | 22.1 | Terrance LivingstonGreat Neck South | Great Neck South '09 | Division 2A Championships | |
| 38 | 22.1 | James McClenicRoosevelt | Roosevelt '09 | 2009 Nassau Coaches Invitational - Boys | |
| 39 | 22.1 | Chike AguFloral Park Memorial | Floral Park Memorial '08 | Class AA County | 2008 |
| 40 | 22.13 | Jaden AntoineHoly Trinity | Holy Trinity '18 | Nassau Coaches Track & Field Invitational | 2018 |
| 41 | 22.14 | Dylan DoneganHicksville | Hicksville | The Jim McGlynn Classic | 2024 |
| 42 | 22.16 | Josiah BrackenMineola | Mineola | Section 8 Class A | 2024 |
| 43 | 22.18 | Brandon RobinsonUniondale | Uniondale '22 | Section VIII State Qualifier | 2022 |
| 44 | 22.18 | Evans LinzeyKellenberg | Kellenberg '24 | NSCHSAA/NSCHSGAA League Championships | 2024 |
| 45 | 22.20 | Tevaughn OwensUniondale | Uniondale '15 | Section VIII Class 3A County Championships | 2015 |
| 46 | 22.2 | Daine WatsonElmont | Elmont '07 | Division IIA | 2005 |
| 47 | 22.2 | Steven KingUniondale | Uniondale '02 | Class A County | 2002 |
| 48 | 22.20 | Alex FrankW. Tresper Clarke | W. Tresper Clarke '26 | Section 8 AA County Championship | 2026 |
| 49 | 22.20 | Tyrell HolderBaldwin | Baldwin '26 | Division 1B Championship | 2026 |
| 50 | 22.20 | Raniel BarrettRoosevelt | Roosevelt '29 | Section 8 AA County Championship | 2026 |
| 51 | 22.22 | Brian Johnson-Norman JrRoosevelt | Roosevelt | Section VIII County Championships Class AA | 2023 |
| 52 | 22.23 | Zaahir ForbesValley Stream Central | Valley Stream Central '18 | Section VIII State Qualifier Meet | 2018 |
| 53 | 22.27 | Kimani LewisElmont Memorial | Elmont Memorial '23 | Section VIII State Qualifier | 2023 |
| 54 | 22.27 | Isaiah JollyMalverne | Malverne | Section 8 A County Championships | 2025 |
| 55 | 22.29 | Nicolas FrattoFarmingdale | Farmingdale '14 | Skyline Track & Field Championships | 2018 |
| 56 | 22.29 | Sedgeley DupervalValley Stream North | Valley Stream North '24 | Valley Stream Challenge Invitational | 2023 |
| 57 | 22.29 | Corey BullRoosevelt | Roosevelt '17 | Section VIII State Qualifier Meet | 2015 |
| 58 | 22.3 | Samuel CuffeySouth Side | South Side '07 | Division 2B Championships | 2006 |
| 59 | 22.3 | Kevin PisciottaMassapequa | Massapequa '07 | Conference IA | 2007 |
| 60 | 22.30 | Rashad TuckerFreeport | Freeport '17 | Nassau Coaches Track & Field Invitational | 2016 |
| 61 | 22.30 | Jordan WilliamsBaldwin | Baldwin '26 | Division 1B Championship | 2026 |
| 62 | 22.3 | Darrel CrearyFreeport | Freeport '05 | State Qualifier | 2005 |
| 63 | 22.3 | Terance MorganRoosevelt | Roosevelt '05 | State Qualifier | 2005 |
| 64 | 22.3 | Nick GubelliBaldwin | Baldwin '03 | Mid Island Invitational | 2003 |
| 65 | 22.3 | Lance KingOceanside | Oceanside '09 | Conference IA | 2007 |
| 66 | 22.33 | Xavier AllenWestbury | Westbury '18 | Section VIII State Qualifier Meet | 2018 |
| 67 | 22.33 | Apollo SimmonsWestbury | Westbury | Section 8 Division 1B Meet | 2024 |
| 68 | 22.35 | Jeremy LissadeMepham | Mepham '17 | Section VIII Division 2A Championships | 2017 |
| 69 | 22.35 | Daniel SantosOceanside | Oceanside | Section VIII Championships Division 1B | 2023 |
| 70 | 22.36 | Brandon FustanioOceanside | Oceanside | Blue and White Invitational | 2025 |
| 71 | 22.361 | Elijah SmithSewanhaka | Sewanhaka '14 | New York State Track & Field Championships | 2014 |
| 72 | 22.38 | Christon RaysorBaldwin | Baldwin | Blue and White Invitational | 2025 |
| 73 | 22.39 | Nico FrattoFarmingdale | Farmingdale '14 | Section VIII Class County Championships | 2014 |
| 74 | 22.40 | Christopher LyonsChaminade | Chaminade '07 | NSCHSAA Spring Track & Field League Championships | 2006 |
| 75 | 22.40 | Derrick IngramUniondale | Uniondale '12 | Knight Time Invitational | 2012 |
| 76 | 22.40 | Richard SemenickChaminade | Chaminade '07 | NSCHSAA Easter Classic | 2007 |
| 77 | 22.4 | Justin RollingUniondale | Uniondale '02 | Class A County | 2002 |
| 78 | 22.4 | Brandon HartleyBaldwin | Baldwin '03 | Class A Counties | 2003 |
| 79 | 22.4 | James LowderRoslyn | Roslyn '02 | Class B County | 2002 |
| 80 | 22.4 | Marques McFarlinMalverne | Malverne '02 | State Qualifier | 2002 |
| 81 | 22.4 | Anthony BarnettUniondale | Uniondale '08 | Division 1A Championships | |
| 82 | 22.4 | Nestor AguiarWest Hempstead | West Hempstead '08 | Division 3B Championships | 2006 |
| 83 | 22.4 | Bovell CarruthersUniondale | Uniondale '07 | Conference IA | 2007 |
| 84 | 22.4 | Matthew DieringerIsland Trees | Island Trees '11 | 2009 Nassau Coaches Invitational - Boys | |
| 85 | 22.42 | DeShaun ThomasFarmingdale | Farmingdale | Farmingdale State College Invitational | 2010 |
| 86 | 22.42 | Cole ThalheimerManhasset | Manhasset | Section 8 Class AA | 2024 |
| 87 | 22.44 | Louis TorresMalverne | Malverne '26 | Section 8 A County Championship | 2026 |
| 88 | 22.45 | Amara KoromaHempstead | Hempstead '19 | Knight Time Invitational | 2018 |
| 89 | 22.45 | Jordan SmithRoslyn | Roslyn | Section VIII Championships Division 2B | 2022 |
| 90 | 22.46 | Joseph VacchioLynbrook | Lynbrook '24 | Section 8 Division 3B Meet | 2024 |
| 91 | 22.46 | Joseph MohauptDivision Avenue | Division Avenue | Nassau Coaches Invitational | 2024 |
| 92 | 22.47 | Romain EcclestonUniondale | Uniondale '26 | Nassau Coaches Invitational | 2026 |
| 93 | 22.48 | Cleveland ModestUniondale | Uniondale '16 | Section VIII Class 3A County Championships | 2015 |
| 94 | 22.49 | Kyle KrummenackerChaminade | Chaminade '19 | Suffolk Coaches Meet | 2019 |
| 95 | 22.50 | Jonathan SpenceSt. Dominic's | St. Dominic's '10 | Post Easter Classic | 2009 |
| 96 | 22.5 | Alix LamarreMepham | Mepham '09 | Class AA County | 2008 |
| 97 | 22.50 | Erin ParkerRoosevelt | Roosevelt '12 | Knight Time Invitational | 2012 |
| 98 | 22.5 | Steven MatthewH. Frank Carey | H. Frank Carey '10 | Division 2A Championships | |
| 99 | 22.5 | Shannon MasonManhasset | Manhasset '07 | Class A Championships | 2006 |
| 100 | 22.50 | Joshua BeloffSacred Heart | Sacred Heart | Stony Brook University - Wolfie Invitational | 2016 |