| 1 | 2:25.96 | Katherine ColonWest Babylon | West Babylon '08 | St. John's University Indoor Invitational | 2012 |
| 2 | 2:31.83 | Lindsey SchwasnicSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 3 | 2:33.10 | Kelly McNicholasWest Islip | West Islip '08 | St. John's University Indoor Invitational | 2012 |
| 4 | 2:33.71 | Shannon ThompsonLindenhurst | Lindenhurst '16 | St Joseph's College Indoor Invitational | 2018 |
| 5 | 2:34.33 | Melanie WalshConnetquot | Connetquot '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 6 | 2:35.97 | Zulena SaraviaBay Shore | Bay Shore '12 | Molloy College Indoor Invitational | 2014 |
| 7 | 2:37.48 | Danielle BuglinoSt. Anthony's | St. Anthony's '14 | Saint Anthony's Girls Developmental Meet | 2013 |
| 8 | 2:40.46 | Marlee LopezBay Shore | Bay Shore '17 | St. John's University Bill Ward Invitational | 2017 |
| 9 | 2:42.08 | Jessica PiernoBellport | Bellport '13 | St. John's University Bill Ward Invitational | 2015 |
| 10 | 2:42.56 | Deborah MyrtilHalf Hollow Hills West | Half Hollow Hills West '13 | St. John's University Bill Ward Invitational | 2014 |
| 11 | 2:42.66 | Francesca LillyShoreham-Wading River | Shoreham-Wading River '19 | Saint Anthony's Girls Developmental Meet | 2013 |
| 12 | 2:42.68 | Tiffanie PierreBay Shore | Bay Shore | USATF Long Island Youth Indoor Track & Field Championships | 2024 |
| 13 | 2:43.39 | Natalia KhourySt. John the Baptist | St. John the Baptist '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 14 | 2:44.40 | Erin MacDonellSayville | Sayville '14 | St Joseph's College Indoor Invitational | 2018 |
| 15 | 2:46.16 | Angelina DesJardiSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 16 | 2:46.19 | Samantha SteeleShoreham-Wading River | Shoreham-Wading River '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 17 | 2:46.72 | Morgan ElliottConnetquot | Connetquot '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 18 | 2:46.76 | Julia FeistBellport | Bellport '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 19 | 2:46.89 | Tanner ScarolaSt. Anthony's | St. Anthony's '22 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 20 | 2:47.00 | Lara Booth AlamConnetquot | Connetquot '24 | Saint Anthony's Developmental Meet 2 | 2019 |
| 21 | 2:47.20 | Sofia CassaraSt. Anthony's | St. Anthony's '23 | Saint Anthony's Developmental Meet 2 | 2019 |
| 22 | 2:48.80 | Aidan NobleSt. Anthony's | St. Anthony's '20 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 23 | 2:49.68 | Taylor VerdiSt. Anthony's | St. Anthony's '21 | Saint Anthony's Boys - Girls Developmental | 2018 |
| 24 | 2:49.99 | Elena BarrySt. Anthony's | St. Anthony's '23 | Saint Anthony's Developmental Meet 2 | 2019 |
| 25 | 2:51.03 | Kaitlyn HennieCentral Islip | Central Islip '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 26 | 2:52.03 | Maria MolnarSt. Anthony's | St. Anthony's '15 | St Joseph's College Indoor Invitational | 2018 |
| 27 | 2:52.49 | Taylor FlanaganShoreham-Wading River | Shoreham-Wading River '17 | Saint Anthony's Girls Developmental Meet | 2013 |
| 28 | 2:55.71 | Osasi AmeneCentral Islip | Central Islip '22 | Saint Anthony's Developmental Meet 2 | 2019 |
| 29 | 2:56.80 | Rudiana AngladeNorth Babylon | North Babylon '14 | St. John's University Bill Ward Invitational | 2015 |
| 30 | 2:57.16 | Christy CapekShoreham-Wading River | Shoreham-Wading River '16 | Saint Anthony's Girls Developmental Meet | 2013 |
| 31 | 2:57.23 | Jennifer O'ConnorLongwood | Longwood '16 | St. John's University Bill Ward Invitational | 2017 |
| 32 | 2:58.09 | Daniela PinzonBay Shore | Bay Shore '16 | St Joseph's College Indoor Invitational | 2018 |
| 33 | 3:00.08 | Emily HaneConnetquot | Connetquot '21 | Saint Anthony's Developmental Meet 2 | 2019 |
| 34 | 3:01.05 | Stephanie SurruscoLongwood | Longwood '16 | St Joseph's College Indoor Invitational | 2018 |
| 35 | 3:04.19 | Sarah DernMercy | Mercy '18 | St. John's University 14th Annual Bill Ward Invitational | 2018 |
| 36 | 3:12.60 | Siera PattersonCentral Islip | Central Islip '20 | Saint Anthony's Developmental Meet 2 | 2019 |
| 37 | 3:15.48 | Stacey SinkoffMount Sinai | Mount Sinai '13 | St. John's University Bill Ward Invitational | 2017 |
| 38 | 3:17.04 | Brittany CollinsConnetquot | Connetquot '12 | St. John's University Bill Ward Invitational | 2014 |
| 39 | 3:33.91 | Monica RodriguezEastport-South Manor | Eastport-South Manor '19 | St. John's University 14th Annual Bill Ward Invitational | 2018 |
| 40 | 3:46.54 | Christina ParrishMount Sinai | Mount Sinai '14 | St. John's University Bill Ward Invitational | 2015 |
